Genetic association studies for complex traits: relevance for the sports medicine practitioner.
نویسنده
چکیده
Disclaimer: BJSM is published by BMJ Publishing Group Ltd (a wholly owned subsidiary of the British Medical Association) and the British Association of Sport and Exercise Medicine. The owners grant editorial freedom to the Editor of BJSM. BJSM follows guidelines on editorial independence produced by the World Association of Medical Editors and the code on good publication practice of the Committee on Publication Ethics.
منابع مشابه
Heritability for Stroke: Essential for Taking Family History
There are many well-established factors that influence the risk of stroke including blood pressure, diabetes, low socioeconomic status and smoking, however, the shared genetic resource in members of a family effect on stroke predisposition. Genome-wide association studies (GWAS) have demonstrated evidence of a shared genetic source in stroke risk. This review considered the influence of family...
متن کاملP30: Are There Anxious Genes?
Anxiety comprises many clinical descriptions and phenotypes. A genetic predisposition to anxiety is undoubted; however, the nature and extent of that contribution is still unclear. Extensive genetic studies of the serotonin (5-hydroxytryptamine, 5-HT) transporter (5-HTT) gene have revealed how variation in gene expression can be correlated with anxiety phenotypes. Complete genome-wide linkage s...
متن کاملIdentification of genomic loci controlling phenologic and morphologic traits in barley (Hordeum vulgare L.) genotypes using association analysis
Association mapping is a technique with high resolution for QTL mapping based on linkage disequilibrium and has shown more promising for describing genetically complex traits. In addition, it is a powerful tool for describing complex agronomic traits and identifying alleles that can contribute to enhance the desired traits. In this study, whole genome association mapping was used in a set of 14...
متن کاملTitle: Sports Genetics Moving Forward -lessons Learned from Medical Research 1 2 Short Running Title: Sports Genetics Moving Forward 3 4
22 Sports genetics can take advantage of lessons learned from human disease genetics. By 23 righting past mistakes and increasing scientific rigor, the breadth and depth of knowledge in 24 the field can be magnified. We present an outline of challenges facing sports genetics in the 25 light of experiences from medical research. 26 Sports performance is complex, resulting from a combination of a...
متن کاملاز ژنوم تا ژن: مروری بر ژن‌ها و تغییرات ژنتیکی موثر بر بروز سندرم متابولیک
Background: The prevalence of non-communicable disorders such as metabolic syndrome (MetS) is high in developing countries. Metabolic syndrome is a disorder of energy utilization and storage, diagnosed by a co-occurrence of three out of five of the following medical conditions: abdominal (central) obesity, elevated blood pressure, elevated fasting plasma glucose, high serum triglycerides, and l...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- British journal of sports medicine
دوره 43 5 شماره
صفحات -
تاریخ انتشار 2009